Vegetables and/or fruit, rich in lutein and colorectal cancer.

Data about lutein-rich vegetables in relation to colon cancer risk was provided by one cohort only. A nonsignificant protective effect among women, but not men was found.

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Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

7) McCullough ML (2003)

The Cancer Prevention Study II Nutrition Cohort.

62,609 men and 70,554 women aged 50-74. (The Nutrition Cohort is a subgroup of the approx. 1.2 million participants in CPS II)

1992-93 to 1997

508 (298 men, 210 women)

colon cancer risk (fatal and nonfatal)

High lutein foods (> 1000 mcg/100 g) (defined as: Broccoli. Spinach. Mustard greens, turnip greens, collards. Green salad)


Men:	Women:
RR = 0.81 (0.55-1.18; P = 0.40) for the highest vs lowest quintile of consumption. Amount specific data (servings/day): < 0.3: RR = 1. 0.3-< 0.5: RR = 0.92 (0.65-1.31). 0.5-< 0.7: RR = 0.71 (0.49-1.01). 0.7-< 1.1: RR = 0.96 (0.69-1.33). ≥ 1.1: RR = 0.81 (0.55-1.18).	RR = 0.67 (0.41-1.10; P = 0.06) for the highest vs lowest quintile of consumption. Amount specific data (servings/day): < 0.3: RR = 1. 0.3-< 0.6: RR = 0.97 (0.66-1.41). 0.6-< 0.8: RR = 0.83 (0.52-1.32). 0.8-< 1.2: RR = 0.76 (0.50-1.17). ≥ 1.2: RR = 0.67 (0.41-1.10).

age, exercise, METs, aspirin, smoking, family history of colorectal cancer, BMI, education, energy, multivitamin use, total calcium and red meat intake. Alcohol intake was not included because it did not influence the effect estimates when entered in the multivariate models.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to colorectal cancer risk & mortality.

Vegetables and/or fruit, rich in lutein and colorectal cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto colorectal cancer risk & mortality.

Vegetables and/or fruit, rich in lutein and colorectal cancer.

Relating various aspects of our diet
to colorectal cancer risk & mortality.