Lung cancer risk: Data about lung cancer risk was provided by 3 cohorts. No associations were found.
Lung cancer mortality: Data about lung cancer mortality was provided by 1 cohort (9). A nonsignificant protective effect was found.
Conclusion: No evidence was found for an association between corn and lung cancer.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments | ||||||||||||||||||||||||||||||||||||||||||||||||
| 29) Wright ME (2008) | The NIH-AARP Diet and Health Study | 472,081 subjects (281,288 men and 190,793 women) aged 50-71. (USA) | 8 (1995-2003) | See variables | Lung cancer risk | Gramineae (corn) |
All men (3,834 cases): RR = 0.96 (0.87-1.06; P = 0.30) for the highest vs lowest quintile of consumption. Amount specific data (servings per 1000 kcal per day): 0.009: RR = 1. 0.03: RR = 0.93 (0.85-1.03). 0.05: RR = 0.98 (0.89-1.08). 0.08: RR = 0.86 (0.78-0.95). 0.16: RR = 0.96 (0.87-1.06).
All women (2,201 cases): RR = 0.91 (0.79-1.04; P = 0.16) for the highest vs lowest quintile of consumption. Amount specific data (servings per 1000 kcal per day): 0.008: RR = 1. 0.03: RR = 0.97 (0.85-1.09). 0.05: RR = 0.99 (0.87-1.12). 0.09: RR = 0.95 (0.84-1.09). 0.17: RR = 0.91 (0.79-1.04).
One serving of vegetables = 1 cup of raw, leafy vegetables, 1/2 cup of other vegetables, or 6 ounces of juice. Age, energy intake, race, education, BMI, smoking status, smoking dose, time since quitting, alcohol intake, physical activity, and family history of any cancer. |
14) Feskanich D (2000) | The Nurses' Health Study | & The Health Professionals' Follow-up Study 77,283 US women (38-63 years) and 47,778 men (40-75 years) | Women: 1984-1996. | Men: 1986-1996. 516? women, and | 258? men Total lung cancer risk | Corn | No significant association with risk (no data shown). | Not defined, but probably: age, follow-up cycle, smoking status,years since quitting among past smokers, cigarettes smoked/day among current smokers, age at start of smoking, total energy intake, and availability of diet data after baseline measure. |
14) Speizer FE (1999) | The Nurses' Health Study. | 89,284 women aged 34-59 years. | (USA) 12 | (1980-1992) 399? | Lung cancer risk | Corn |
RR = 0.5 (No 95% CI; P = 0.18) for the highest vs the lowest quintile of consumption. | Amount specific data (Frequency of consumption): Never: RR = 1. 1-3/mo: RR = 0.8. 1/wk: RR = 0.8. 2-4/wk: RR = 0.8. ≥ 5/wk: RR = 0.5. age, smoking (past, current, amount in 1980), and age of starting to smoke |
|