Onions and ovarian cancer.
Data about onions was provided by 3 cohorts. No associations were found with ovarian cancer risk.
Data about onions was provided by 3 cohorts. No associations were found with ovarian cancer risk.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 13) Wang L (2009) | The Women's Health Study | 38,408 female health professionals aged ≥ 45. (USA) | 11.5 (1992-95 to 2007) | 141? | Ovarian cancer incidence | Onion | Risk did not materially change with intake (data not shown). | Age, race, total energy, randomized treatment assignment, smoking, alcohol use, physical activity, postmenopausal status, hormone replacement therapy use, multivitamin use, family history of colorectal cancer, ovary cancer, or breast cancer, and intake of fruit and vegetables, fiber, folate, and saturated fat. |
| 7) Mommers M (2005) | The Netherlands Cohort Study | 62,573 postmenopausal women aged 55-69. | 11,3 (1986-1997) | 240? | Invasive epithelial ovarian cancer incidence | Onions | RR = 0.93 (0.75-1.16) per 25-g per day increment. | Age, height, current cigarette smoking, duration of cigarette smoking, number of cigarettes smoked daily, duration of oral contraceptive use, parity, and all individual fruit or vegetable items listed. |
| 4) Gates MA (2007) | The Nurses' Health Study | 66,940 women aged 38-63. (USA) | 18 (1984-2002) | 347 | Epithelial ovarian cancer risk | Onions |
RR = 0.78 (0.47-1.30; P = 0.56) for the highest vs lowest quintile of consumption. Amount specific data (Servings: < 2/month: RR = 1. 2/month-< 1/week: RR = 1.08 (0.81-1.43). 1/week: RR = 1.19 (0.89-1.60). 2-3/week: RR = 0.95 (0.66-1.36). 4+/week: RR = 0.78 (0.47-1.30). | Age, duration of oral contraceptive use, parity, history of tubal ligation, smoking status, history of postmenopausal hormone use, physical activity, lactose intake, and total energy intake. |