Yellow fruits and pancreatic cancer.

Pancreatic cancer risk: Data about the relation with pancreatic cancer risk was provided by one cohort (16). No association was found.

Pancreatic cancer mortality: Data about the relation with pancreatic cancer mortality was provided by one cohort with very few cancer cases (1). A nonsignificant protective effect was found.

Conclusion: No significant associations were found. No evidence was found for an association between yellow fruits and pancreatic cancer.

Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
16) Nöthlings U (2007)	The Multiethnic Cohort Study	162,150 subjects (72,966 men and 89,184 women) aged 45-75. (Hawaii-Los Angeles)	8 (1993-96 to 2002)	434	Exocrine pancreatic cancer incidence	Yellow-orange fruit (not defined)	RR = 1.16 (0.87-1.54; P = 0.19) for the highest vs lowest quartile of consumption. Amount specific data (g/1000 kcal./d): < 6.0: RR = 1. 6.0-14.7: RR = 0.98 (0.74-1.30). 14.7-35.1: RR = 1.10 (0.83-1.46). ≥ 35.1: RR = 1.16 (0.87-1.54). -The intake of yellow-orange fruit was positively associated with pancreatic cancer risk among normal-weight participants. -There was little evidence of effect modification by smoking status (never, former, or current).	Controlled for sex and time on study. Adjusted for race-ethnicity, age at cohort entry, smoking status, pack-years of smoking, family history of pancreatic cancer, energy intake, intakes of red meat and processed meat, and BMI.
1) Mills PK (1988)	The Adventist Health Study	34,198 non-Hispanic white California Seventh-day Adventists aged ≥ 25.	1976-82	40?	Pancreas cancer death	Fresh winter fruit (apples, bananas, pears)	A nonsignificant protective effect (no data shown).	Age and sex.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

16) Nöthlings U (2007)

The Multiethnic Cohort Study

162,150 subjects (72,966 men and 89,184 women) aged 45-75.
(Hawaii-Los Angeles)

8
(1993-96 to 2002)

434

Exocrine pancreatic cancer incidence

Yellow-orange fruit (not defined)

RR = 1.16 (0.87-1.54; P = 0.19) for the highest vs lowest quartile of consumption.

Amount specific data (g/1000 kcal./d):
< 6.0: RR = 1.
6.0-14.7: RR = 0.98 (0.74-1.30).
14.7-35.1: RR = 1.10 (0.83-1.46).
≥ 35.1: RR = 1.16 (0.87-1.54).

-The intake of yellow-orange fruit was positively associated with pancreatic cancer risk among normal-weight participants.
-There was little evidence of effect modification by smoking status (never, former, or current).

Controlled for sex and time on study. Adjusted for race-ethnicity, age at cohort entry, smoking status, pack-years of smoking, family history of pancreatic cancer, energy intake, intakes of red meat and processed meat, and BMI.

1) Mills PK (1988)

The Adventist Health Study

34,198 non-Hispanic white California Seventh-day Adventists aged ≥ 25.

1976-82

40?

Pancreas cancer death

Fresh winter fruit (apples, bananas, pears)

A nonsignificant protective effect (no data shown).

Age and sex.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to pancreatic cancer risk & mortality.

Yellow fruits and pancreatic cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto pancreatic cancer risk & mortality.

Yellow fruits and pancreatic cancer.

Relating various aspects of our diet
to pancreatic cancer risk & mortality.