Data about allium vegetables was provided by 1 cohort. A significant protective effect (trend) was found in the Spanish part of the cohort, but not among individuals
with diabetes mellitus in the total cohort.
Conclusion: A significant protective effect was found in one subcohort. No evidence was found for an association between allium vegetables and mortality.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 21) Nöthlings U (2008) | The EPIC Study. | 10,449 participants - aged 35 to 70- with self-reported diabetes mellitus. (10 European Countries) | 9 (1992-2000 to 2007) | 1346? | All-cause mortality | Garlic/onion vegetables | RR = 0.97 (0.87-1.10) for an increase of 8 g/d. | Stratified on age. Adusted for sex, smoking status, self-reported heart attack at baseline, self-reported hypertension at baseline, self-reported cancer at baseline, waist-to-hip ratio, insulin treatment, age at diabetes diagnosis, energy intake, alcohol intake. |
| 21) Agudo A. (2007) | The EPIC Study. | 41,358 subjects (15,610 men, and 25,748 women) aged 30-69. (Spain) | 6.5 (1992-96 to 2002) | 562? (295 cancer, and 123 CVD) | All cause mortality | Onion and garlic (not defined) |
HR = 0.82 (0.64-1.06; P = 0.047) for the highest vs lowest quartile of consumption. Amount specific data (median intake in g/day): 5.7: HR = 1. 13.7: HR = 1.13 (0.89-1.43). 24.0: HR = 0.93 (0.73-1.19). 43.6: HR = 0.82 (0.64-1.06). HR as a continuous variable: HR = 0.97 (0.90-1.05). There was no effect modification by sex. | Stratified by center. Adjusted for age, sex, total energy, education, BMI, physical activity, cigarette smoking, and alcohol. |